The practical applicability of in-house structure determination using Cr Kα X-rays (2.29 A˚) and a loopless free crystal mounting method was examined using five novel proteins. Proteins from 9.6 to 84 kDa have been solved using this method without any derivatization. In all cases, more than 90% of structures were constructed automatically with side chains by use of the Cr SAD method. The free crystal mounting technique increases the accuracy of the anomalous differences between Bijvoet mates and makes the in-house single-wavelength SAD method with a Cr Kα X-ray source a very useful tool for high-throughput structure determination. In addition, a Cr/Cu dual-wavelength system makes it possible to perform structure analysis from phasing to refinement of the structure in-house.
A customized single crystal X-ray diffraction system that has the capabilities of utilizing both ports of a rotating anode X-ray source.
A microfocus sealed tube single crystal X-ray diffractometer that is low maintenance and perfect for screening and evaluating protein crystals.
A single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator and direct detection, HPC X-ray detector.
A versatile and high-flux dual-wavelength (DW) X-ray diffractometer with an HPC X-ray detector for multipurpose diffraction experiments
Single wavelength Confocal Max-Flux (CMF) optics for single crystal diffraction
Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers
Small angle X-ray scattering (SAXS) Kratky camera system
User-inspired data collection and data processing software for small molecule and protein crystallography
Robotic sample changer to provide unattended data acquisition, enhanced productivity and standardized workflow to your research environment.
A unique curved single crystal X-ray diffraction detector based on direct X-ray detection technology with the highest 2θ range at a single position available for the home lab.
Extremely low noise, air-cooled X-ray detector based on direct X-ray detection technology.
High-resolution X-ray detectors for X-ray diffractometers from DECTRIS