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Pharmaceuticals

Pharmaceuticals

Elemental / phase analysis to molecular structure

In medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and designed. In the recent past, most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery. A new approach, using so-called "rational drug design", has been to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge. Given this importance, Rigaku has been at the forefront in the development of single crystal diffraction for both macromolecular and small molecule structure determination. Rigaku products range from crystal diffraction screening and high-resolution data collection systems to 3D structure refinement and imaging software.

X-ray powder diffraction is extensively used in the drug discovery, design, development and formulation processes to obtain critical knowledge about pharmaceutical products. Many parameters required by the FDA, legal patent issues and drug performance are only accessible by employing XRD. With the introduction of systems specifically developed with the pharmaceutical industry in mind, XRD is now both cost-effective and easy-to-use. Phase analysis and polymorph identification are common analytical needs within both pharmaceutical development and production. In addition, crystal structure determination, the study of non-ambient behavior, and overall morphology help to provide a complete understanding of the properties of a pharmaceutical agent.

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熱分析装置

X線回折装置(XRD)

X線回折装置(XRD), 熱分析装置

単結晶X線構造解析 低分子関連装置

水晶・単結晶方位測定

発生ガス分析装置, 熱分析装置

リガクの関連装置


WDXRF

Benchtop tube below sequential WDXRF spectrometer analyzes O through U in solids, liquids and powders

High power, tube below, sequential WDXRF spectrometer with Smart Sample Loading System (SSLS)

High power, tube above, sequential WDXRF spectrometer with new ZSX Guidance expert system software

High power, tube above, sequential WDXRF spectrometer

WDXRF spectrometer designed to handle very large and/or heavy samples

High-throughput tube-above multi-channel simultaneous WDXRF spectrometer analyzes Be through U

Tube below, single element WDXRF analyzer for quality control applications

High power, tube above, sequential WDXRF spectrometer

High power, tube above, sequential WDXRF spectrometer

Small Molecule

Our most popular diffractometer for chemical crystallography, configured with either single or dual microfocus sealed tube X-ray sources and an extremely low noise direct X-ray detection detector.

A benchtop single crystal X-ray diffractometer ideal for self-service crystallography and teaching.

A modern single crystal X-ray diffractometer for structural analysis of small molecule samples configured with microfocus sealed tube technology and a direct X-ray detection detector.

An extremely high-flux rotating anode X-ray diffractometer specifically configured for measuring difficult samples.

A dual-wavelength, extremely high-flux, rotating anode X-ray diffractometer specifically configured for measuring difficult samples as well as providing versatility through multiple wavelengths.

User-inspired data collection and data processing software for small molecule and protein crystallography

A bespoke, extremely high-flux diffractometer with custom enclosure and the flexibility to utilize both ports of the rotating anode X-ray source.

The smallest detachable motorized goniometer head on the market

Robotic sample changer to provide unattended data acquisition, enhanced productivity and standardized workflow to your research environment.

A new and fully integrated electron diffractometer for measuring submicron crystals, utilizing a seamless workflow from data collection to structure determination of crystal structures

X線回折装置(XRD)

New 6th-generation general purpose benchtop XRD system for phase i.d and phase quantification

Highly versatile multipurpose X-ray diffractometer with built-in intelligent guidance

High-performance, multi-purpose XRD system for applications ranging from R&D to quality control

Raman

Handheld Raman for raw material identification and finished product authentication using 1064 nm Raman analysis.

Protein

Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers

Automated crystal transport, orientation and retrieval robot

A customized single crystal X-ray diffraction system that has the capabilities of utilizing both ports of a rotating anode X-ray source.

A microfocus sealed tube single crystal X-ray diffractometer that is low maintenance and perfect for screening and evaluating protein crystals.

A single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator and direct detection, HPC X-ray detector.

A versatile and high-flux dual-wavelength (DW) X-ray diffractometer with an HPC X-ray detector for multipurpose diffraction experiments

EDXRF

Performance EDXRF elemental analyzer measures Na to U in solids, liquids, powders and thin-films

New variable collimator small spot 60 kV EDXRF system featuring QuantEZ software.

EDXRF spectrometer with powerful Windows® software and optional FP.

High-performance, Cartesian-geometry EDXRF elemental analyzer measures Na to U in solids, liquids, powders and thin films

Detectors

PILATUS3 R hybrid pixel array detector (HPAD) for X-ray crystallography

2D X-ray detector with latest semiconductor technology designed for home lab diffractometers

Extremely low noise, compact, air-cooled X-ray detector based on direct X-ray detection technology.

A unique curved single crystal X-ray diffraction detector based on direct X-ray detection technology with the highest 2θ range at a single position available for the home lab.

小角散乱測定装置(SAXS)

Small angle X-ray scattering (SAXS) Kratky camera system

X-ray CT

High-speed, stationary sample microtomography of large samples

Ultra-high resolution nanotomography using parallel beam geometry

High-resolution benchtop microtomography of large samples

Thermal Analysis

TG-DTA is a hyphenated technology generally referred to as simultaneous thermal analysis (STA).

 

 

TG-DTA is a hyphenated technology generally referred to as simultaneous thermal analysis (STA).

 

 

TG-DTA is a hyphenated technology generally referred to as simultaneous thermal analysis (STA).

 

 

TG-DTA is a hyphenated technology generally referred to as simultaneous thermal analysis (STA).

 

 

TG-DTA is a hyphenated technology generally referred to as simultaneous thermal analysis (STA).